antiarrhythmic agent — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T72323	Antiarrhythmic agent-1
	Antiarrhythmic agent-1 (example I), functioning as an antiarrhythmic agent and an IKr potassium channel blocker (IC 50 <1 μM), effectively inhibits cardiac arrhythmias.
T23652	AFD-21	AFD21,NS-2 Class 1 antiarrhythmic agent
	AFD-21 is a class I antiarrhythmic drug. It binds to sodium channels in their inactivated state and exerts use- and voltage-dependent inhibition of sodium channels with unbinding rates comparable to those of class I anti...
T6476	Dofetilide	UK 68789,UK-68798,Tikosyn	Potassium Channel
	Dofetilide (UK 68789) is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ik...		Potassium Channel
T0866	Propafenone	Rythmol,Propafenonum	Potassium Channel , MRP , Sodium Channel
	Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity....		Potassium Channel , MRP , Sodium Channel
T11099	Droxicainide		Others
	Droxicainide is an antiarrhythmic agent.		Others
T24021	E 0747	E-0747,E0747
	E 0747 is an antiarrhythmic agent of class 1C type. E-0747 suppresses arrhythmia by inhibiting the Na channels of cardiac cells.
T0249	N-Acetylprocainamide	NAPA,Acecainide	Potassium Channel , Sodium Channel , Drug Metabolite
	N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmic drug.		Potassium Channel , Sodium Channel , Drug Metabolite
T12858	Bidisomide	SC40230	Others
	Bidisomide (SC40230) is an agent of class I antiarrhythmic.		Others
T4539	Nicainoprol	RU-42924	Sodium Channel
	Nicainoprol (RU-42924) is a fast-sodium-channel blocking drug. Nicainoprol is a potent antiarrhythmic agent.		Sodium Channel
T1334	Hydroquinidine	Hydroconchinine,Dihydroquinidine,Hydroconquinine,(+)-Hydroquinidine,Dihydroquinine	Potassium Channel , Sodium Channel
	Hydroquinidine ((+)-Hydroquinidine) is an organic compound, used as an antiarrhythmic agent.		Potassium Channel , Sodium Channel
T0792	(-)-Sparteine sulfate pentahydrate	(-)-Sparteine Sulfate,Lupinidine sulfate pentahydrate,(-)-Sparteine sulfate salt,sulfate pentahydrate	Sodium Channel
	(-)-Sparteine sulfate pentahydrate ((-)-Sparteine Sulfate) is a class 1a antiarrhythmic agent and a sodium channel blocker. It can chelate the bivalents calcium and magnesium.		Sodium Channel
T7219	Flecainide acetate	Flecainide (acetate),R-818	Sodium Channel
	Flecainide acetate (R-818) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormal fast rhythms of the heart).		Sodium Channel
T7938	Quinidine		Parasite
	Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.		Parasite
T7198	E-4031		EGFR , Potassium Channel
	E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)		EGFR , Potassium Channel
T7505	Azimilide Dihydrochloride	NE-10064 Dihydrochloride	Potassium Channel
	Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the slowly activating (IKs) and rapidly activating (IKr) components of the delayed rectifier potassium current		Potassium Channel
T7853	(+)-Sparteine	Pachycarpine	AChR
	(+)-Sparteine (Pachycarpine) is a natural product extracted from scotch broom, is a sodium channel blocker and a class 1a antiarrhythmic agent		AChR
T60322	Procainamide	Biocoryl,Novocainamide	DNA Methyltransferase
	Procainamide (Novocainamide) is a specific and potent DNA methyltransferase 1 ( DNMT1 ) inhibitor. Procainamide is a Class 1A antiarrhythmic agent. Procainamide has the potential for the research of cancer and arrhythmia...		DNA Methyltransferase
T11353	Gallopamil	Methoxyverapamil	Calcium Channel
	Gallopamil (Methoxyverapamil) inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM. Gallopamil is a potent antiarrhythmic and vasodilator agent. Gallopamil (Methoxyverapamil), a methoxy der...		Calcium Channel
T13177	Taquidil
	Tocainide hydrochloride is a sodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is an orally effective antiarrhythmic agent, structurally and ...
T0802	Procaine hydrochloride	Novocaine HCl,Procaine HCl	Histone Demethylase , 5-HT Receptor , DNA/RNA Synthesis , Sodium Channel , NMDAR , AChR
	Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannel...